Inhibition of Human and Mouse 17<i>β</i>-HSD2 by 2,5-Thiophene Amide, 1,3-Phenyl Amide and 1,4-Phenyl Amide Derivatives in a Cell-Free Assay.
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aMean value of at least two determinations, standard deviation less than 20%. bHuman placental microsomal fraction, substrate E2 [500 nM], cofactor NAD+ [1500 μM]. cMouse liver microsomal fraction, substrate E2 [500 nM], cofactor NAD+ [1500 μM]. dn.i.: no inhibition, i.e., inhibition ≤10%. Inhibition of Human and Mouse 17β-HSD2 by 2,5-Thiophene Amide, 1,3-Phenyl Amide and 1,4-Phenyl Amide Derivatives in a Cell-Free Assay.
创建时间：
2015-07-31
