Taking full advantage of PacBio SMRT sequencing used for the genome assembly and detected DNA methylation on a genome-wide scale and analyzing all base modifications to determine modified sequence mot

NIAID Data Ecosystem00

MBD-Seq was applied to study the CpG methylation map of immortallyzed human myoblasts after DiPRO1/ZNF555 inhibition. MBD-Seq was applied to study the CpG methylation map of immortallyzed human myoblasts after DiPRO1/ZNF555 inhibition

DNA甲基化分析

ZNF555基因功能

The methylation enrichment was determined by MIRA-sequencing after MBD2-capture using the MethylCollector™ Ultra Kit (Active Motif) performed on DNA samples derived from immortallized human myoblasts.

NIAID Data Ecosystem00

DNA methylation in Syrian hamster female fetal cells (gestation day 13.5) exposed in vitro to 5-aza-2'deoxycytidine (5aCdR)

DNA甲基化分析

表观遗传毒理学

Purpose: To validate the reduced representation bisulfite sequencing (RRBS) methodology by comparing DNA methylation pattern in Syrian hamster fetal (SHF) primary cells to a SHF cell line (MT2) expose

NIAID Data Ecosystem10

Natural depletion of H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation

转座子调控

DNA甲基化分析

Transposable elements (TEs) are largely inactive. Interestingly, a subset of TEs are naturally expressed in the vegetative cell (VC) of the male gametophyte, pollen in Arabidopsis. However, the extent

NIAID Data Ecosystem00

5-hydroxymethylcytosine-mediated epigenetic modifications between iPSCs and hESCs

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