Atomic Structure of a Short α-Helix Stabilized by a Main Chain Hydrogen-Bond Surrogate
收藏NIAID Data Ecosystem2026-03-06 收录
下载链接:
https://figshare.com/articles/dataset/Atomic_Structure_of_a_Short_Helix_Stabilized_by_a_Main_Chain_Hydrogen_Bond_Surrogate/2947831
下载链接
链接失效反馈官方服务:
资源简介:
Herein we report the 1.15 Å X-ray crystal structure of a short α-helix in which the N-terminal i
and i + 4 main chain hydrogen bond is replaced with a carbon−carbon bond. The structure shows that the
hydrogen-bond surrogate (HBS) derived α-helix truly resembles the structure of canonical α-helices and
provides unequivocal support for our helix nucleation strategy.
创建时间:
2016-06-03



