Background: Tuberculosis, mainly caused by Mycobacterium tuberculosis (Mtb), is an ancient human disease that gravely affects millions of people annually. We wanted to explore the genetic diversity an

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M. tuberculosis bioinformatics training data

分枝杆菌基因组与基因表达

变异检测与注释

Training data based on for tutorial on M. tuberculosis variant calling and annotation based on inferred ancestral reference genome of M. tuberculosis combined with NCBI NC_000962.3 annotation

Zenodo2020-07-24 更新00

Mycobacterium tuberculosis genome sequencing for variant calling benchmarking

基因组基准测试

分枝杆菌基因组与基因表达

PacBio sequencing was used to sequence and assembly genomes from clinical M. tuberculosis isolates. The PacBio genome assemblies were then used to benchmark variant calling performance of short-read I

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Overview of all SNP diversity detected in the cluster, the visual grading of the SNPs and the distribution of the diverse identified in the clustered isolates in the NL database of 3981 isolates.. * = relative to the reference genome H37Rv (AL123456.3).

分枝杆菌基因组与基因表达

SNP变异分析

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