2D numerical mouse phantom for dynamic photoacoustic tomography virtual imaging studies of small animal models

Companion data set of manuscript: Luke Lozenski, Mark Anastasio, and Umberto Villa. A Memory-Efficient Dynamic Image Reconstruction Method using Neural Fields. Arxiv-2205.05585, 2022 This dataset provides anatomically realistic spatiotemporal maps of optical absorption coefficient and photoacoustically induced pressure distribution for virtual imaging studies of dynamic photoacoustic tomography of small animal models. Physical dimensions of the 2D-plus-time object are 2.9 cm x 2.9 cm and a 5 seconds time horizon (corresponding to a full breathing cycle). The object is rendered on a spatiotemporal Cartesian grid with 400 x 400 pixels and 180 time frames. The anatomical information of the spatiotemporal object is derived from a two-dimensional (2D) cardio-torso slice extracted from an anatomically realistic whole-body murine numerical phantom (MOBY, Segars et Al, 2004). MOBY comprises detailed three-dimensional (3D) anatomical structures featuring tens of organs and models physiologically realistic cardiac and respiratory motions. Each organ/tissue was then assigned a plausible value of the optical absorption coefficient in the near-infrared range. The optical scattering coefficient was then assumed to be constant throughout the object. For each time frame, the photoacoustically induced pressure distribution was simulated by solving the diffusion approximation to the radiative transport equations with uniform illumination. The data set consists of the following files: induced_pressure.mat: Induced pressure map on cardio-torso slice of murine phantom optical_absorption.mat: Optical absorption map on cardio-torso slice of murine phantom This dataset was saved as a MATLAB binary file version 5 (extension .mat). It can be imported in MATLAB using the load function. For more information about the MOBY phantom and how to obtain it, please see https://otc.duke.edu/technologies/4d-mouse-whole-body-moby-phantom-version-2-0/