The self-renewal of gastric cancer stem cells is regulated by a specific collaboration between the microenvironment and the genetic condition.. Homo sapiens

Because cancer stem cells already had genetic and epigenetic alterations which can affect the self-renewal, we tried to characterize genetic and epigenetic changes of the gastric cancer stem cells. To do this, we performed SNP array, MBD sequencing and RNA sequencing. Overall design: copy number alteration profiles of Normal tissue and gastric cancer stem cell were generated by SNP6.0 Array, in three patients(csc1,csc2,csc3).