Crystal structure of the MerTK kinase domain with SA4488
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Crystal structure of the MerTK kinase domain with SA4488 Descriptor: (5P)-2-amino-5-(1-methyl-1H-pyrazol-4-yl)-N-{(1R,2S)-2-[(4'-{2-[4-(2-oxoethyl)piperazin-1-yl]propan-2-yl}[1,1'-biphenyl]-4-yl)methoxy]cyclopentyl}pyridine-3-carboxamide, CHLORIDE ION, Mer tyrosine kinase domain Authors: Jakob, C.G, Qui, W, Jain, R. Deposit date: 2024-04-20 Release date: 2024-10-09 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor. J.Med.Chem., 67, 2024
创建时间：
2024-04-20
