Inter-locus polyQ toxicity and expandability of the dynamic DNA polyQ loci.

athe coefficient of correlation (r) of age-at-onset versus repeat length was obtained by fitting an exponential decay model to each dataset (see Figure 1 & Figure S1). All correlations were highly significant (Pbrepeat length corresponding to an age at onset of 32 years.csex-averaged intergenerational expandability of each disorder as previously described [31].CI; Confidence Interval.