Changes of haemodynamic and biochemical parameters in control and lipopolysaccharide (LPS) groups.

Depicted are changes of mean arterial pressure (MAP), heart rate (HR), alanine aminotransferase (ALT), creatinine (CRE), blood urea nitrogen (BUN), lactate dehydrogenase (LDH) and nitric oxide (NO) in control group (0.9% NaCl, infusion 10 min, n = 8) and LPS groups (lipopolysaccharide, LPS 10 mg/kg; infusion 10 min, n = 8 in each group). The LPS groups were further divided into 4 groups, which were sacrificed at 1 h after LPS (LPS1h), at 2 h after LPS (LPS2h), at 4 h after LPS (LPS4h) and at 6 h after LPS (LPS6h), separately. Data are expressed as mean ± SEM.*P