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Aberrant gene expression leakage from linage-specific heterochromatic loci during senescence [RNA-seq]

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NIAID Data Ecosystem2026-03-13 收录
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To understand induction of cornification genes during lineage appropriate (keratinocyte differentiation) and inappropriate (fibroblast senescence) conditions , we generated histone modification and gene expression datasets. Then we compared keratinocyte's datasets with fibroblast senescence ones in this study. Overall design: RNA-seq datasets were generated for control and p16-senescence IMR90 cells, as well as control and RAS-induced senescence keratinocytes.

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2021-10-25
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