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Genome-wide Virus-integration Analysis Reveals A Common Oncogenic Insertional Mechanism of HPV, HBV and EBV. viral metagenome

NIAID Data Ecosystem2026-03-12 收录

病毒整合分析

肿瘤病毒学

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA664651 数据链接链接失效反馈

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Genome-wide Virus-integration Analysis Reveals A Common Oncogenic Insertional Mechanism of HPV, HBV and EBV

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创建时间：

2020-09-21

肿瘤病毒学

皮肤黑色素瘤

As immunosuppressed patients often develop multiple independent non-melanoma skin cancers, we reasoned that viruses consistently present in independent tumors might be more likely to be involved in tu

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KSHV Manipulates Notch Signaling by Upregulating Dll4 and JAG1 to Alter Cell Cycle Gene Expression in LECs

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Notch信号通路

Kaposi sarcoma is the most common cancer in AIDS patients and is typified by red skin lesions. The disease is caused by the KSHV virus (HHV8) and is recognizable by its distinctive red skin lesions. T

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Inactivation of p53 but Not p73 by Adenovirus Type 5 E1B 55-Kilodalton and E4 34-Kilodalton Oncoproteins

肿瘤病毒学

p53突变调控机制

The adenovirus E1B 55-kDa and E4 34-kDa oncoproteins bind and inactivate the p53 tumor suppressor gene product, resulting in cell transformation. A recently discovered cellular protein, p73, shows ext

PubMed Central20

Widespread traces of lytic KSHV in primary effusion lymphoma at single-cell resolution

肿瘤病毒学

单细胞转录组学

Cancer cells of primary effusion lymphoma (PEL) often contain both Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). We measured the interplay of human, KSHV, and EBV transcri

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Table_2_A First NGS Investigation Suggests No Association Between Viruses and Canine Cancers.xlsx

肿瘤基因组学

病毒整合分析

Approximately 10–15% of worldwide human cancers are attributable to viral infection. When operating as carcinogenic elements, viruses may act with various mechanisms, but the most important is represe

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Genome-wide Virus-integration Analysis Reveals A Common Oncogenic Insertional Mechanism of HPV, HBV and EBV. viral metagenome

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