Gene expression changes of dipropylene glycol-induced in renal cortex of rats. Rattus norvegicus

This study is to develop a short term and highly accurate prediction method of renal carcinogenicity based on gene expression profile of rats administrated by carcinogens. We conducted 28 days-repeated dose experiments in male SD rats with dipropylene glycol, and the gene expression profiles of renal cortex were analyzed using custom microarrays. Overall design: Experimental design is the two group (control group vs. dipropylene glycol treated group). Three biological replicates were performed for each group.