Pseudoalteromonas piscicida strain:DE2-B Genome sequencing and assembly

Pseudoalteromonas piscicida strain DE2-B is a naturally occurring, Gram-negative, marine Gammaproteobacterium that was isolated from seawater from the Delaware coast (USA). It produces antimicrobial compounds that have a broad spectrum of inhibitory activities against human and fish pathogens including vibrios. Pseudoalteromonas spp. have been used as probiotics to reduce pathogens in aquaculture and has been shown to reduce biofilm formation. In this study, we fully sequenced and annotated P. piscicida strain DE2-B to further elucidate the genome and to facilitate research on compounds that are inhibitory toward other Gram-negative as well as Gram-positive bacteria.

伪假单胞菌属鱼类病原体菌株DE2-B是一种自然存在的革兰氏阴性海洋伽马变形菌，该菌株源自美国特拉华海岸的海水。该菌株能够产生具有广泛抑菌活性的化合物，能够抑制包括弧菌在内的人类和鱼类病原体。伪假单胞菌属（Pseudoalteromonas spp.）被用作益生菌以降低水产养殖中的病原体，并已被证明可减少生物膜的形成。在本研究中，我们对P. piscicida菌株DE2-B进行了全序列测序和注释，以进一步阐明其基因组结构，并便于开展针对其他革兰氏阴性菌以及革兰氏阳性菌的抑菌化合物的研究。