Distribution of the 68 R. felis pRF plasmid ORFs within the OGs predicted by OrthoMCLA.

AResults include 44 predicted ORFs from the putative smaller R. felis plasmid, pRF�� (see Gillespie et al., 2007).BFollows Gillespie et al. (2007). Additional annotation is listed below in footnotes G-Z.CBlank values depict R. felis singletons.DBold OGs depict singletons upon the removal of doubtful orthologs from pRF��. Italicized OGs Blast to chromosomal proteins on the R. felis chromosome.EUnderlined OGs contain more than one pRF ORF.FRepresentative (R) or non-representative (N) family. Groups containing ORFs from pRF�� are noted with an asterisk.GHP.HType I restriction enzyme EcoEI M protein.ICHP.JThe pRF�� protein in PATRIC, VBI0166RF3_0019, is slightly different than the pRF protein.KConjugal transfer protein TraA.LPutative transposase.MDNA polymerase III polC-typeNTransposase for insertion sequence element IS1328.OR46 site-specific recombinase, Transposon Tn917 resolvase.PISBma2, transposase.QTransposon Tn917 resolvase, R46 site-specific recombinase.RThe pRF�� protein in PATRIC, VBI0166RF3_0020, is slightly different than the pRF protein.SProbable transposase for transposon Tn903.TCOG1396: Predicted transcriptional regulators.UCOG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain.VProtein virD4.WSpore protein SP21.XProbable transposase for insertion sequence element.YCell division cycle protein 27 homolog.ZMyosin-11 (R. prowazekii), M protein, serotype 2.1 precursor (R. typhi).