Co-crystal Structure of sEH with tetrahydroberberine derivative

Co-crystal Structure of sEH with tetrahydroberberine derivative Descriptor: 1-[(13~{a}~{R})-2,3-dimethoxy-6,8,13,13~{a}-tetrahydro-5~{H}-isoquinolino[3,2-a]isoquinolin-10-yl]-3-[[4-(trifluoromethyloxy)phenyl]methyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... Authors: Wang, H, Feng, Y, Du, X.Y. Deposit date: 2024-09-04 Release date: 2025-09-10 Last modified: 2026-04-01 Method: X-RAY DIFFRACTION (3.13 Å) Cite: Redesigning Berberines and Sanguinarines to Target Soluble Epoxide Hydrolase for Enhanced Anti-Inflammatory Efficacy. J.Med.Chem., 67, 2024