Supporting Information S1 - Has the Rate of CD4 Cell Count Decline before Initiation of Antiretroviral Therapy Changed over the Course of the Dutch HIV Epidemic among MSM?
To assess the prognostic value of baseline HIV-1 DNA levels, a meta-analysis was conducted according to the PROSPERO protocol (CRD42024619050) based on data from studies published until March 4, 2025.
Data from Review of Symptoms Form [CRF 7] Study Description ATN 026 investigated the association between HLA class I genotypes and differing HIV-1 disease progression. The study assessed HIV-1 specifi
aHomogeneous patient group: MSM from W-Europe/N-America. Patients with non-B subtype infection excluded.bAdjusted for gender, region of origin, subtype, age at seroconversion, HIV transmission group,
Median durations of follow-up across studies and datapoints were 4.8 years for AIDS depending on RNA; 6.3 years for death depending on RNA; 4.9 years for AIDS depending on CD4, and 4.6 years for death
