Mantpy datasets for spatial extracellular-matrix analysis

Datasets for spatial extracellular-matrix (ECM) analysis with Mantpy, as used in the Mantpy paper. This version adds the second human small-intestine image and removes the prostate H&E/Visium tutorial archive (still available in version 0.2.0); the other three archives are byte-identical to version 0.2.0. Exact sizes and SHA-256 of all archives are in mantpy-datasets-manifest.json; each archive also carries an inner manifest. mantpy-coliv-intestine.tar.gz: human small intestine image 1 (collagen IV; HuBMAP HBM926.SHNZ.594), raw TIFF, held-out five-layer reference and quick-start assets. Its inner manifest names HuBMAP HBM893.MCGS.487; the image is pixel-identical to HBM926.SHNZ.594. mantpy-hbm735-intestine.tar.gz (new): human small intestine image 2 (HuBMAP HBM735.PSTF.274), the native-resolution collagen IV plane (uint16, 9,514 × 9,994 pixels, 0.37744 µm per pixel) and a manual four-class anatomical annotation (villus, crypts, muscularis mucosae, submucosa). mantpy-balbc-pbs-lung.tar.gz: BALB/c PBS mouse lung imaging mass cytometry, six raw OME-TIFF stacks, typed-cell H5AD inputs, panel and de-identified metadata. mantpy-schistosoma-ecm.tar.gz: Schistosoma mansoni-infected and naive mouse liver imaging mass cytometry, 24 raw imaging stacks, panel and de-identified mouse/ROI metadata. Loading. Mantpy 1.0.2 loads the image-1, lung and liver archives from version 0.2.0 of this record (record 21538382), whose files it pins by size and SHA-256 (mt.datasets.coliv_intestine(), mt.datasets.balbc_pbs_lung(), mt.datasets.schistosoma_ecm()). The image-2 archive is read by the reproduction notebooks, which verify its SHA-256; it uses the same flat layout and manifest schema as the other archives. HuBMAP data. The intestine images are derived from HuBMAP CODEX data, published under CC BY 4.0 and governed by the HuBMAP External Data Sharing Policy; users must not use the data to identify or contact donors. The results here are in whole or part based upon data generated by the HuBMAP Program. Please cite: HuBMAP Consortium. The human body at cellular resolution: the NIH Human Biomolecular Atlas Program. Nature 574, 187–192 (2019). https://doi.org/10.1038/s41586-019-1629-x For use of these datasets please also cite: BALB/c PBS lung: Parkinson, J.E., Bryant, M., Ghafoor, M. et al. Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation. Mol Syst Biol (2026). https://doi.org/10.1038/s44320-026-00234-5. Schistosoma ECM: Su, K. et al. SOX9 plays an essential role in myofibroblast driven hepatic granuloma integrity and parenchymal repair during schistosomiasis-induced liver damage. PLoS Pathogens 21(6) (2025). https://doi.org/10.1371/journal.ppat.1012928