HOXB13, HOXA11 and HOXA11-AS transcriptome regulation in prostate cancer cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE147710
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资源简介：
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression, playing fundamental roles in cancer development. We analyzed changes in transcriptome profiling in prostate cancer PC-3 cells transfected with siRNAs targeting lncRNA HOXA11-AS, its upstream regulator HOXB13 and its opposite strand protein coding gene HOXA11. PC-3 cells were transfected for 24h or 48 h with 20 uM siRNAs targeting HOXB13, HOXA11-AS or HOXA11. siRNAs targeting two different sequences were combined for more efficient gene silencing and downstream effects. Total RNA was extracted with NucleoSpin Plus (MHN) and sent for microarray analysis.
创建时间：
2021-03-10
