Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5l87
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Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. Descriptor: 1,2-ETHANEDIOL, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, Peroxin 14 Authors: Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. Deposit date: 2016-06-07 Release date: 2017-03-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (0.87 Å) Cite: Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science, 355, 2017
创建时间：
2016-06-07
