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DARATUMUMAB, A NOVEL THERAPEUTIC HUMAN CD38 MONOCLONAL ANTIBODY, INDUCES KILLING OF MULTIPLE MYELOMA AND OTHER HEMATOLOGICAL TUMORS

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Harvard Dataverse2024-01-01 更新2026-04-09 收录
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A presentation on a potential anti-CD38 mAb, daratumumab which stood out from a panel of selected 42 human mAbs that specifically bound to CD38-transfected CHO cells (CHO-CD38) was identified. By competition binding experiments on CHO-CD38 cells, mAbs were divide into four competition groups from 1-4 i.e., HM-037, HM-003, daratumumab, and HM-029 respectively.

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2024-01-01
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