Myelofibrosis as a result of myeloproliferative disease - Male, 67 - Tissue image [11290630017284791]

This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 67Clinical description: A patient diagnosed four years earlier with polycythemia vera (JAK2 positive in molecular tests).
Currently in a physical examination hepatosplenomegaly.
In additional tests, anemia with leukoerythroblastosis, LDH - 500 U / L.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: CHRONIC MYELOPROLIFERATIVE DISORDERSDiagnosis: Myelofibrosis as a result of myeloproliferative diseaseResult of the histopathological examination: Post policythaemia vera myelofibrosis (postPV-MF)
Gomori - reticulin fibrosis increased (MF = 2);
Diffuse and dense increase in reticulin with extensive intersections,.Sample:Material: FFPECollecting method: Bone marrow biopsyTopography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSOrgan: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSTissue: Bone marrowType of staining: positive/HCStaining: Gomori Silver Impregnation (Reticulum)Antibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk