five

12q amplification in liposarcoma

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP149509
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资源简介:
A cohort of liposarcomas with either rod-shaped markers or ring chromosomes was analyzed with regard to copy number variation. In cases with co-amplification of other chromosomes, the data suggested a stepwise process, starting with gain of parts of chromosome 12, followed by cycles of BFB events. Co-amplification with other chromosomes seems to occur through the formation of dicentric chromosomes. The data also suggest that some lipomas could develop into WDLS through stepwise gain of 12q material.
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2024-07-21
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