Activation of p63 initiates quality control programs in oocytes

Specialized surveillance mechanisms are essential to maintain the genetic integrity of germ cells, which are not only the source of all somatic cells but also of the germ cells of the next generation. DNA damage and chromosomal aberrations are, therefore, For differential expression analysis RNA-Seq experiments of mouse were used containing five different points of time (0h, 1h, 2h30min., 4h, 6h) after irradiation wth 0.5 and 0.2 Gy respectively. 30bp single-end reads of RNA-Seq samples on illumina HiSeq.