C. elegans Embryonic Differentiation Tree (10 division events)

Differentiation tree (Gordon, 1999) of Caenorhabditis elegans (Nematode, roundworm) embryo up to 10 division events. Data from lineage trees and fate maps of Sulston and Horvitz (1977) and Hobert (2010). Division event timing approximated from Bhatla (2016). Cell size information approximated from Bao et.al (2006).A division event occurs when a mother cell divides into two daughter cells. In rare instances, a mother cell only produces a single daughter cell. In this case, no size information is available for the daughter cell. According to the differentiation tree convention, smaller cells are placed to the left and larger cells are placed to the right. Each cell is annotated with its standard nomenclature and a decimal value that describes the relative size of each daughter cell (e.g. smaller cell is 0.49, larger cell is 0.51).References:Bao, Z.R.; Murray, J.I.; Boyle, T.; Ooi, S.L.; Sandel, M.J.; Waterston, R.H. 2006. Automated cell lineage tracing in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America, 103, 2707-2712.Bhatla, N. 2016. C. elegans Cell Lineage. WormWeb, http://wormweb.org/celllineage Accessed on 2/12/2016.Hobert O. 2010. Neurogenesis in the nematode Caenorhabditis elegans. WormBook, doi:10.1895/ wormbook.1.12.2.Sulston, J.E. and Horvitz, H.R. 1977. Post-embryonic cell lineages of the nematode Caenorhabditis elegans. Developmental Biology, 56, 110-156.

Caenorhabditis elegans（线虫，蛔虫）胚胎分化树（Gordon，1999）直至10次分裂事件。数据来源于Sulston和Horvitz（1977）以及Hobert（2010）的谱系树和命运图谱。分裂事件的时间估计来自Bhatla（2016）。细胞大小信息估计来自Bao等（2006）。当母细胞分裂成两个子细胞时，即发生分裂事件。在罕见情况下，母细胞仅产生一个子细胞。在这种情况下，子细胞的大小信息不可用。根据分化树惯例，较小的细胞置于左侧，较大的细胞置于右侧。每个细胞均附有其标准命名法以及描述每个子细胞相对大小的十进制值（例如，较小的细胞为0.49，较大的细胞为0.51）。参考文献：Bao, Z.R.；Murray, J.I.；Boyle, T.；Ooi, S.L.；Sandel, M.J.；Waterston, R.H. 2006. 在Caenorhabditis elegans中的自动化细胞谱系追踪。美国国家科学院院刊，103，2707-2712。Bhatla, N. 2016. C. elegans 细胞谱系。WormWeb，http://wormweb.org/celllineage 访问时间：2016年2月12日。Hobert O. 2010. 线虫Caenorhabditis elegans中的神经发生。WormBook，doi:10.1895/wormbook.1.12.2。Sulston, J.E. 和 Horvitz, H.R. 1977. 线虫Caenorhabditis elegans的胚胎后细胞谱系。发育生物学，56，110-156。