REG3A binds bacterial phospholipids

Structural studies of human REG3A by X-ray diffraction with electron microscopy suggest that REG3A binds to bacterial membrane phospholipids and kills bacteria by forming a hexameric membrane-permeabilizing pore (Mukherjee S et al. 2014).通过对人类REG3A的X射线衍射与电子显微镜结构研究，揭示了REG3A与细菌细胞膜磷脂的结合及其通过形成六聚体膜穿透孔（Mukherjee S 等人，2014年）来杀灭细菌的机制。