Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity
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https://www.ncbi.nlm.nih.gov/sra/SRP119707
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资源简介：
DAG-activated Pkd1 promotes triglyceride accumulation in adipocytes; Pkd1 promotes lipogenesis and suppresses mitochondrial function in adipocytes in an AMPK-dependent manner; Pkd1 suppresses expression of genes characteristic for beige adipocytes; Deletion of Pkd1 in adipocytes protects mice from diet-induced obesity, T2D and liver steatosis. Overall design: Gene expression changes in subcutaneous adipose tissue of mice after deletion of Pkd1.
创建时间：
2019-09-23
