CryoEM structure of miniGq-coupled hM3Dq in complex with CNO
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CryoEM structure of miniGq-coupled hM3Dq in complex with CNO Descriptor: 8-chloro-11-(4-methyl-4-oxo-4lambda~5~-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Zhang, S, Fay, J.F, Roth, B.L. Deposit date: 2022-08-27 Release date: 2022-11-30 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: Molecular basis for selective activation of DREADD-based chemogenetics. Nature, 612, 2022
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2022-08-27
