相关数据集
Gene and protein sequence features augment HLA class I ligand predictions (mRNA sequencing)
The sensitivity of malignant tissues to T cell-based cancer immunotherapies is dependent on the presence of targetable HLA class I ligands on the tumor cell surface. Peptide intrinsic factors, such as
NIAID Data Ecosystem100
Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands.
The epitope was eluted from human B-lymphoblastoid cell lines expressing full-length or truncated HLA A*02:01 gene such that they express membrane-bound and secreted HLA A*02:01, or JETHOM cells.
ImmuneData30
Exploiting trogocytosis by Immunopeptidomics to profile tumor associated antigens (TAA) actively targeted by tumor specific T cells in leukemia.
We employed PeptiCHIP Immunopeptidomics to profile tumor associated antigens (TAA) actively targeted by tumor specific T cells by exploiting the trogocytosis effect, whereby antigen presenting cells (
NIAID Data Ecosystem20
T Cell Responses to Known Allergen Proteins Are Differently Polarized and Account for a Variable Fraction of Total Response to Allergen Extracts
epitope description:GCIHMARSLANEWRD antigen name:Cla h 8 mhc allele name:HLA-DPB1*20:01
ImmuneData30
Selective pre-priming of HA-specific CD4 T cells restores immunological reactivity to HA on heterosubtypic influenza infection.
CD4 T cell responses directed against the epitope were greatly diminished in the spleen at 8 days following secondary infection compared to the responses following a primary infection.
ImmuneData30
