STAT5 plays a critical role in mediating cellular responses following cytokine stimulation. The activated STAT5 proteins can form dimers and tetramers with distinct biological functions. The role of S
Using transcriptional profiling in retinae of experimental autoimmune encephalitis (EAE) in CX3CR1GFP/+ knock-in mice, we are able to show two distinct waves of innate immune cell activation separated
BHLHE40 is a transcription factor regulating proinflammatory cytokines such as granulocyte-macrophage colony-stimulating factor (GM-CSF) in CD4+ T cells. Although implicated in autoimmune inflammation