Plasma lipids levels of rats fed with STD or CD with or without a GSPE and/or DHA-OR in chronic treatments.

Abbreviations: GSPE, grape seed proanthocyanidin extracts; CD, cafeteria-diet; STD, standard chow diet; DHA-OR, oil-rich in docosahexaenoic acid; TG, triacylglyceride; TC, total cholesterol. Rats were fed with STD (STD group) or with STD plus CD for 10 weeks. After 10 weeks, rats fed a STD plus a CD were orally treated with 25 mg GSPE/kg bw (CD+GSPE), 515 mg PUFAs/kg bw (CD+DHA-OR), 25 mg GSPE and 515 mg ω-3 PUFAs/kg bw (CD+GSPE+DHA-OR group) or vehicle (CD control group) for 3 weeks simultaneously with the CD. Each value is the mean ± s.e.m. of seven rats. Letters denotes a significant difference between groups (p<0.05; One-way ANOVA).