Structure and Thermodynamics of N6-methyladenosine in RNA: a Spring-Loaded Base Modification

NIAID Data Ecosystem2026-03-10 收录

RNA表观转录组学

m6A修饰位点鉴定

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP052910 数据链接链接失效反馈

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资源简介：

We determine m6A modification sites in GM12878 cells. Overall design: Examination of m6A modification sites on the transcriptome of GM12878 cells, using a m6A-specific antibody.

创建时间：

2017-09-17

meCLICK-Seq - substrate-hijacking and RNA degradation strategy for the study of RNA methylation. meCLICK-Seq - substrate-hijacking and RNA degradation strategy for the study of RNA methylation

甲基化测序

m6A修饰位点鉴定

The method hijacks RNA methyltransferase activity to introduce an alkyne, instead of a methyl, moiety on RNA. Subsequent copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) with an imidazole-degrad

NIAID Data Ecosystem80

Source data for a strand-aware RNA modification x ncRNA precursor atlas

RNA表观转录组学

非编码RNA修饰图谱

This dataset contains the source data and reproducible analysis package for a strand-aware RNA modification x ncRNA precursor atlas based on hg38/GRCh38 coordinates. The package includes the RNA modif

Zenodo2026-06-12 更新10

A Study of Post-transcriptional m6A Modification. Tang et al.

RNA表观转录组学

转录后修饰

Here, we develop 4sU-m6A-level and isoform-characterization sequencing (4sU-m6A-LAIC-seq) and 4sU-GLORI, designed to quantify the m6A levels for both newly synthesized and steady-state RNAs at transcr

Mendeley Data00

Lack of TRMT2A, a tRNA methyltransferase, induces the generation of tRNA-derived small RNAs due to m5U54 tRNA hypomodification [Seq]. Lack of TRMT2A, a tRNA methyltransferase, induces the generation of tRNA-derived small RNAs due to m5U54 tRNA hypomodification [Seq]

RNA表观转录组学

tRNA衍生小RNA生成机制

Transfer RNA (tRNA) molecules contain a variety of post-transcriptional modifications which are crucial for tRNA stability, translation efficiency, and fidelity. Besides their canonical roles in trans

NIAID Data Ecosystem40

Table1_Transcriptome-wide 1-methyladenosine functional profiling of messenger RNA and long non-coding RNA in bladder cancer.XLSX

膀胱癌m1A修饰

RNA表观转录组学

Introduction: Post-transcriptional RNA modifications are crucial regulators of tumor development and progression. In many biological processes, N1-methyladenosine (m1A) plays a key role. However, litt

NIAID Data Ecosystem10

Structure and Thermodynamics of N6-methyladenosine in RNA: a Spring-Loaded Base Modification

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