HUMAN PI3KDELTA IN COMPLEX WITH PYRIDAZINONE INHIBITOR 7
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HUMAN PI3KDELTA IN COMPLEX WITH PYRIDAZINONE INHIBITOR 7 Descriptor: 5-[(1~{S})-1-[4-azanyl-3-(5-oxidanylpyridin-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-4-cyclopentyl-2-(phenylmethyl)pyridazin-3-one, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Authors: Pala, D, Bruno, P, Capelli, A.M, Biagetti, M. Deposit date: 2024-02-20 Release date: 2024-07-03 Last modified: 2024-07-24 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Discovery and Optimization of Pyridazinones as PI3K delta Selective Inhibitors for Administration by Inhalation. J.Med.Chem., 67, 2024
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2024-02-20
