Evaluation of Rheum ribes L. aqueous extract effect on neuropathy

Intervention 1: Intervention group: Patients randomly enter the intervention group, and use 5 ml of the prescribed extract for 7 days from the second day of chemotherapy until the seventh course of chemotherapy. Intervention 2: Control group: Patients randomly enter the control group, and use 5 ml of the placebo for 7 days from the second day of chemotherapy until the seventh course of chemotherapy. Primary outcome(s): . Peripheral neuropathy. Timepoint: End of day 7 after each chemotherapy course until the seventh term of chemotherapy. Method of measurement: questionnaire. Study Design: Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Double blind, Blinding description: Double blind.