Examine the effects of mutations in two paralogous type-1 myosins in the model organism Saccharomyces cerevisiae on the evolution of the endocytosis protein interaction network.
This data contains fitness values for PPAT protein mutants described in:Plesa C, Sidore AM, Lubock N, Zhang D, Kosuri S. Multiplexed Gene Synthesis in Emulsions for Exploring Protein Functional Landsc
The NDM-1 metallo-beta-lactamase (MBL) was mutated to all single amino acid mutants, then placed under selection with 3 antibiotics (ampicillin, cefotaxime, meropenem) to characterize the mutants' fun
