Data from: Apparent selection pressure for dynamic range and channel capacity in bacterial chemotactic sensors
收藏DataCite Commons2026-04-27 更新2026-04-25 收录
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https://datadryad.org/dataset/doi:10.5061/dryad.wpzgmsc3j
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资源简介:
Bacterial chemotactic sensing converts noisy chemical signals into running
and tumbling. We analyze the static sensing limits of mixed Tar/Tsr
chemoreceptor clusters in individual Escherichia coli cells using a
heterogeneous Monod–Wyman–Changeux (MWC) model. By sweeping a
seven-dimensional parameter space, we compute three sensing performance
metrics—channel capacity, dynamic range, and effective Hill coefficient.
Across E. coli–like parameter regimes, we consistently observe pronounced
global maxima of channel capacity and global maxima of the related dynamic
range, whereas the effective Hill coefficient does not exhibit comparable
optimization. The capacity-achieving input distribution is bimodal, which
implies that individual cells maximize information by sampling both low-
and high-concentration regimes. Together, these results suggest that, at
the individual-cell level, channel capacity and dynamic range may be
selected for in E. coli receptor clusters.
提供机构:
Dryad
创建时间:
2026-03-03



