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Effect of PTX3 on gene expression of THP-1 macrophages

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE227402
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We aimed to investigate the effect of PTX3 on macrophages functions. After PTX3 stimulation for 18 h in THP-1 macrophages, total RNA were harvested for RNA-seq analysis of ctrl (n = 1) and PTX3 group (n = 1). THP-1 macrophage differentiation was induced by treatment of 320 nM PMA for 6 h. THP-1 macrophages were then treated with or without 50 ng/ml PTX3 for 18 h (Ctrl, n =1 and PTX3, n = 1) and the RNA lysates were harvested for comparative gene expression profiling analysis of RNA-seq data.
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2023-03-20
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