Pseudostellaria heterophylla polysaccharides for the treatment of diabetes-related lower extremity ischemia.

Diabetic lower limb ischemia (DLLI), a severe complication of diabetic macrovascular disease, presents significant therapeutic challenges. Exploring the novel mechanisms of Pseudostellaria heterophylla polysaccharides in treating DLLI will provide valuable insights for developing natural drugs targeting diabetic microvascular lesions and offer potential therapeutic value for clinical treatment.