Cryo-EM structure of CRISPR-associated cA4 bound Cat1 Pentagonal filament assembly

Cryo-EM structure of CRISPR-associated cA4 bound Cat1 Pentagonal filament assembly Descriptor: Cat1 (CRISPR associated TIR 1) pentagonal filament, RNA (5'-R(P*AP*AP*AP*A)-3') Authors: Majumder, P, Patel, D.J. Deposit date: 2025-01-13 Release date: 2025-04-16 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cat1 forms filament networks to degrade NAD + during the type III CRISPR-Cas antiviral response. Science, 388, 2025