Virus infection induces the production of type I and type II interferons (IFN-I and IFN-II), cytokines that mediate the antiviral response. IFN-I (IFN-a and -b) induces the assembly of ISGF3 (interfer

NIAID Data Ecosystem20

IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection

蝙蝠抗病毒免疫

干扰素信号通路

Bats are important reservoirs of many viruses, which are capable of infecting the host without inducing obvious clinical diseases. Interferon and the downstream interferon regulated genes (IRGs) are k

Figshare2017-08-10 更新10

Chromatin profiling of GM12878 cells with and without a predicted enhancer element

增强子功能验证

干扰素信号通路

We test the predicted interferon-inducible enhancer activity of a LINE within the first intron of the IFNAR1 gene (IFNAR1.L1M2a) by knocking out the predicted enhancer using CRISPR, and assessing chro

NIAID Data Ecosystem20

MDA5-binding interferon-inducible RNA sequencing

MDA5-RNA相互作用鉴定

干扰素信号通路

The goal is to assess whether interferon-inducible RNA regulates type I IFN through cytosolic RNA sensor MDA5. Huh7 cells were treated with or without IFN beta. Anti-MDA5 immunoprecipitation was condu

NIAID Data Ecosystem20

Type-I interferome in human peripheral blood mononuclear cells (PBMC)

资源简介：

相关数据集