Co-Crystal Structure of MDM2 with Inhibitor Compound 4
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Co-Crystal Structure of MDM2 with Inhibitor Compound 4 Descriptor: (2-{[(3R,5R,6S)-1-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]methyl}-1,3-thiazol-5-yl)acetic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION Authors: Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. Deposit date: 2014-01-10 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres. J.Med.Chem., 57, 2014
创建时间：
2014-01-10
