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CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity [scRNA-seq]

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NIAID Data Ecosystem2026-03-13 收录
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Integrative system approaches uncover a three-tier system for the regulatory modules of nutrient signaling-dependent mTORC1 activation in regulatory T cells Overall design: We used scRNA-seq to profile CD45+YFP+ Treg cells, CD45+YFP-CD11b- non-Treg cells and CD45+CD11b+ myeloid cells (mixed at 1:2:1 ratio) in the MC38 colon adenocarcinoma

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2021-11-25
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