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Raw dataset of seminal proteomic from obesity and diabetes rats

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NIAID Data Ecosystem2026-03-12 收录
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https://data.mendeley.com/datasets/rfp7kfjcsd
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资源简介:
Study question: The obesity and diabetes induced in a male rodent can change proteome of spermatozoa? What data shows: These data show the sperm cells profile proteomic of 30 male Wistar rats, separated into 3 groups, control (n = 10), obese (n = 10) and diabetics (n = 09). Rats were fed with commercial food provided controllably to control group and diabetic group or hypercaloric diet added 5% sucrose in ad libitum water to obese group, for 38 weeks. The diabetic group was induced with 35 mg / kg of streptozotocin, 53 days before euthanasia, respecting the spermatogenesis cycle. After euthanasia, sperm were collected and were separated of the seminal plasma by centrifugation and prepared individually for proteomic analysis by ESI Q-Tof mass spectrometer. How the data can be interpreted: There are three folders in the dataset, separated by control, diabetic and obese groups, with all quantified sperm cell proteins, per animal, properly identified.
创建时间:
2020-10-06
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