Expression of dTip60E431Q using the pan-neuronal elav-GAL4 driver leads to lethality.

*p≤0.05.aTest Cross Fly Lines. Five male flies homozygous for either dTip60E431Q or dTip60WT P-element insertions or control w1118 were mated to 10 female virgin flies homozygous for the pan-neuronal elav-GAL4 driver located on chromosome X. Adult progeny were counted over an eight day period and the total male (GAL4−) and female (GAL4+) numbers were scored.bNumber of Surviving Flies. Both dTIP60E431Q lines showed significant lethality, with 25% survival for line A and 0% survival for line B and C. Both dTIP60WT lines showed no observable phenotypic effects. The results are reported as mean ± SD, (n = 3).