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Cumulative in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse Hoxd cluster [ChIP-seq]

NIAID Data Ecosystem2026-03-13 收录

CTCF结合位点功能验证

Hox基因簇调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP331015 数据链接链接失效反馈

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资源简介：

ChIP-seq analysis of CTCF wildtype in mouse embryonic posterior trunk and brain samples Overall design: ChIP-seq analysis of CTCF wildtype in mouse embryonic posterior trunk and brain samples

应用场景：

创建时间：

2021-11-19

合成基因组重构

Hox基因簇调控

Precise Hox gene expression is crucial for embryonic patterning. Local transcription factor binding and distal enhancer elements have emerged as the major regulatory modes controlling the initiation a

NIAID Data Ecosystem30

CRISPR and biochemical screens identify MAZ as a co-factor in CTCF-mediated insulation at Hox clusters [MAZ KO]. CRISPR and biochemical screens identify MAZ as a co-factor in CTCF-mediated insulation at Hox clusters [MAZ KO]

CTCF绝缘机制

Hox基因簇调控

In this experiment, we sought to analyze how transcriptome of WT and MAZ knock-out (KO) cells change during differentiation of mouse embryonic stem cells (ESCs) into cervical motor neurons (MNs) Overa

NIAID Data Ecosystem30

CRISPR and biochemical screens Identify MAZ as a co-factor in CTCF-mediated insulation at Hox Clusters [CRISPR_set9]

CTCF介导绝缘作用

Hox基因簇调控

In this experiment, we sought to analyze the genes positively or negatively selected during differentiation of mouse embryonic stem cells (ESCs) into cervical motor neurons (MNs) with particular focus

NIAID Data Ecosystem20

Cumulative in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse Hoxd cluster [ChIP-seq]. Cumulative in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse Hoxd cluster [ChIP-seq]

CTCF功能基因组学

Hox基因簇调控

ChIP-seq analysis of CTCF wildtype in mouse embryonic posterior trunk and brain samples Overall design: ChIP-seq analysis of CTCF wildtype in mouse embryonic posterior trunk and brain samples

NIAID Data Ecosystem30

Constrained transcriptional polarity in the organization of mammalian Hox gene clusters (Strand specific RNA-seq). Constrained transcriptional polarity in the organization of mammalian Hox gene clusters (Strand specific RNA-seq)

Hox基因簇调控

链特异性转录组学

In many animal species with a bilateral symmetry, Hox genes are clustered either at one or at several genomic loci. This organization has a functional relevance, for the transcriptional control applie

NIAID Data Ecosystem20

Cumulative in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse Hoxd cluster [ChIP-seq]

资源简介：

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