Analysis of peptide 121–145 and its deletions for prediction to bind HLA-DR alleles and secretion of IFN-γ by PBMCs from HLA-DR heterogeneous healthy subjects.

HLA types of donors 1(DR7,17,52,53; DQ2,6), 3(DR11,13,52; DQ7), 4(DR17,52; DQ2) 5(DR1,18,52;DQ4,5), 6(DR14,15,51,52; DQ5,6), 7(DR4,16,51,53;DQ5,8), 8(DR4,17,52,53;DQ2,8).The regions of peptide 121–145 and its deletions predicted to bind HLA-DR molecules are shown in bold and the anchor sequences are underlined.aP/T = Number of positive PBMCs donors/Number of donors tested.bNA = Not applicable. This is because these sequences are [27].