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Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, local
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, local Descriptor: CHOLESTEROL, Mas-related G-protein coupled receptor member X2, peptide from Pro-adrenomedullin Authors: Li,
Protein Data Bank Japan2024-10-23 更新30
Development of Potent and Selective Antagonists for the UTP-Activated P2Y4 Receptor
P2Y4 is a Gq protein-coupled receptor activated by uridine-5′-triphosphate (UTP), which is widely expressed in the body, e.g., in intestine, heart, and brain. No selective P2Y4 receptor antagonist has
Figshare2017-03-30 更新20
Discovery of Potent and Brain-Penetrant Inverse Agonists for GPR61, an Orphan G Protein-Coupled Receptor
GPR61 is a class A orphan G protein-coupled receptor (GPCR) that is predominantly expressed in the pituitary gland and appetite-regulating centers of the brain. Genome-wide association analysis, epige
Figshare20
Insights into unbound–bound states of GPR142 receptor in a membrane-aqueous system using molecular dynamics simulations
G protein coupled receptors (GPCRs) are source machinery in signal transduction pathways and being one of the major therapeutic targets play a significant in drug discovery. GPR142, an orphan GPCR, ha
Figshare2018-04-21 更新20
Binding parameters of CHO-K1 cells expressing human CMKLR1, GPR1 or CCRL2.
Binding parameters of CHO-K1 cells expressing human CMKLR1, GPR1 or CCRL2.
NIAID Data Ecosystem20
