No evidence of clinical or subclinical infection following inoculation of rPrP-res into mice with different genetic backgrounds.

aMice inoculated with a 1∶10 dilution of a 22L mouse scrapie 10% brain homogenate. These mice were not inoculated in the same experiment as the rPrP-res inoculated mice.bBrains and spleens of two mice tested negative for PrPSc at 200, 365, and 626 dpi.cBrains and spleens of two mice tested negative for PrPSc at 365 dpi.dBrains and spleens of three mice tested negative for PrPSc at 367 dpi.eNumbers in parentheses represent the number of scrapie positive mice over the total number of mice inoculated.fdays post-inoculation (DPI). Numbers represent either average incubation time + SD or days post-inoculation when the experiment was terminated.