Long non-coding RNA LIPTER effect on human iPSC-CMs and mouse heart. Long non-coding RNA LIPTER effect on human iPSC-CMs and mouse heart

Long non-coding RNA LIPTER effect on human iPSC-CMs and mouse heart Overall design: Analysis of human lncRNA LIPTER effect on human WT or LIPTER KO iPSC-CMs. which were cultured in high glucose DMEM for 40 days. To analyse the LIPTER effect in vivo, WT and LIPTER transgenic mice were fed with high fat diet for 7 months. And then heart RNA profile were analyzed by RNA-seq. Results provide the LIPTER functiions on both human iPSC-CMs and mouse heart.