Structure of human CK2 alpha kinase (catalytic subunit) with the inhibitor 108600.
收藏Protein Data Bank Japan2026-04-15 更新2026-03-21 收录
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Structure of human CK2 alpha kinase (catalytic subunit) with the inhibitor 108600. Descriptor: (2Z)-6-[(2,6-dichlorophenyl)methanesulfonyl]-2-[(4-hydroxy-3-nitrophenyl)methylidene]-2H-1,4-benzothiazin-3(4H)-one, Casein kinase II subunit alpha, GLYCEROL, ... Authors: Rechkoblit, O, Aggarwal, A.K. Deposit date: 2020-12-15 Release date: 2021-08-11 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease. Nat Commun, 12, 2021
创建时间：
2020-12-15
