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Crystal structure of human TLR8 in complex with CU-CPT8m

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of human TLR8 in complex with CU-CPT8m Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, ... Authors: Tanji, H, Ohto, U, Shimizu, T. Deposit date: 2017-01-16 Release date: 2017-12-13 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Small-molecule inhibition of TLR8 through stabilization of its resting state Nat. Chem. Biol., 14, 2018

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2017-01-16
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